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Venlafaxine ER (generic Effexor)


Venlafaxine (generic Effexor) extended-release is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD) (excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance. Off-label uses include the treatment of diabetic neuropathy, migraine prevention and hot flashes (hot flushes; sudden strong feelings of heat and sweating) in women who have experienced menopause or who are taking medication to treat breast cancer.

Quantity/Dose Price Medical Services Fee Shipping Total
30  25mg Tablet$ 25.00$ 39.95$ 4.99$ 69.94
60  25mg Tablet$ 35.00$ 39.95$ 4.99$ 79.94
90  25mg Tablet$ 45.00$ 39.95$ 4.99$ 89.94
30  50mg Tablet$ 26.00$ 39.95$ 4.99$ 70.94
60  50mg Tablet$ 36.00$ 39.95$ 4.99$ 80.94
90  50mg Tablet$ 46.00$ 39.95$ 4.99$ 90.94

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IMPORTANT NOTE: This information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other health care provider. It should not be construed to indicate that the use of the medication(s) shown are safe, appropriate, or effective for you. The information shown is general and does not cover all directions, possible drug integrations, or precautions. Information on this site cannot be used for self-treatment and/or self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care provider. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site nor will we be held responsible for consequences of self-treatment. Consult your health care provider before using any drug.

Drug Facts for Venlafaxine / Generic Effexor

Alternate Names:
Effexor

Uses:
Venlafaxine (generic Effexor) extended-release is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (GAD) (excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance. Off-label uses include the treatment of diabetic neuropathy, migraine prevention and hot flashes (hot flushes; sudden strong feelings of heat and sweating) in women who have experienced menopause or who are taking medication to treat breast cancer.

IMPORTANT WARNING:
A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as venlafaxine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take venlafaxine, but in some cases, a doctor may decide that venlafaxine is the best medication to treat a child's condition. You should know that your mental health may change in unexpected ways when you take venlafaxine or other antidepressants even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own. Your healthcare provider will want to see you often while you are taking venlafaxine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor. The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with venlafaxine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/UCM096273. No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

How to Use:
Venlafaxine comes as a tablet or extended-release capsule to take by mouth. The tablet is usually taken two or three times a day with food. The extended-release capsule is usually taken once daily in the morning or evening with food. Take venlafaxine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take venlafaxine exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.
Swallow the extended-release capsule whole; do not split, chew, or crush it, or place it in water. If you cannot swallow the extended-release capsule, you may carefully open the capsule and sprinkle the entire contents on a spoonful of applesauce. Swallow (without chewing) this mixture immediately after preparation and then drink a glass of water to make sure that you have swallowed all of the medication.
Your doctor will probably start you on a low dose of venlafaxine and gradually increase your dose, not more often than once every 4 to 7 days. Tell your doctor how you are feeling during your treatment so that your doctor can adjust your dose properly.
Venlafaxine controls depression but does not cure it. It may take 6 to 8 weeks or longer for you to feel the full benefit of this medication. Continue to take venlafaxine even if you feel well. Do not stop taking venlafaxine without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking venlafaxine, you may experience withdrawal symptoms such as agitation; anxiety; confusion; sad mood; irritability; frenzied or abnormal excitement; lack of coordination; trouble falling asleep or staying asleep; nightmares; nausea; vomiting; loss of appetite; diarrhea; dry mouth; sweating; ringing in the ears; seizures; or burning, tingling, numbness, or electric shock-like feelings in any part of the body. Tell your doctor if you experience any of these symptoms while you are decreasing your dose of venlafaxine or soon after you stop taking venlafaxine.

Side Effects:
Venlafaxine may cause side effects. Call your doctor if any of the following symptoms are severe or do not go away:
  • drowsiness
  • weakness or tiredness
  • dizziness
  • headache
  • nightmares
  • nausea
  • vomiting
  • stomach pain
  • constipation
  • diarrhea
  • gas
  • heartburn
  • burping
  • dry mouth
  • change in ability to taste food
  • loss of appetite
  • weight loss
  • uncontrollable shaking of a part of the body
  • pain, burning, numbness, or tingling in part of the body
  • muscle tightness
  • twitching
  • yawning
  • sweating
  • hot flashes or flushing
  • frequent urination
  • difficulty urinating
  • sore throat, chills, or other signs of infection
  • ringing in the ears
  • changes in sexual desire or ability
  • enlarged pupils (black circles in the middle of the eyes)
Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • chest pain
  • fast, pounding, or irregular heartbeat
  • seizures
  • unusual bruising or bleeding
  • small purple spots on the skin
  • eye pain or redness
  • changes in vision
  • fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness
  • fever
  • problems with coordination
  • hallucinations (seeing things or hearing voices that do not exist)
  • coma (loss of consciousness for a period of time)
Venlafaxine may slow growth and weight gain in children. If your child is taking venlafaxine, your child's doctor will watch your child's growth carefully. Talk to your child's doctor about the risks of giving venlafaxine to your child.

Venlafaxine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

Precautions:
Tell your health care provider if you are taking a monoamine oxidase (MAO) inhibitor, such as:
  • isocarboxazid (Marplan)
  • phenelzine (Nardil)
  • selegiline (Eldepryl, Emsam, Zelapar)
  • tranylcypromine (Parnate)
If you have stopped taking a MAO inhibitor within the past 14 days, your doctor will probably tell you that you should not take venlafaxine. If you stop taking venlafaxine, your doctor will tell you that you should wait at least 7 days before you start to take a MAO inhibitor.

Tell your health care provider if you are taking any of the following:
  • anticoagulants ('blood thinners') such as warfarin (Coumadin)
  • amiodarone (Cordarone, Pacerone)
  • other antidepressants
  • cimetidine (Tagamet)
  • clozapine (Clozaril)
  • diuretics ('water pills')
  • duloxetine (Cymbalta)
  • haloperidol (Haldol)
  • imipramine (Tofranil)
  • indinavir (Crixivan)
  • ketoconazole (Nizoral)
  • linezolid (Zyvox)
  • lithium
  • medications for anxiety, mental illness, pain, seizures, or weight loss
  • medications for migraine such as:
    • almotriptan (Axert)
    • eletriptan (Relpax)
    • frovatriptan (Frova)
    • naratriptan (Amerge)
    • rizatriptan (Maxalt)
    • sumatriptan (Imitrex)
    • zolmitriptan (Zomig)
  • methadone (Dolophine)
  • methylene blue
  • phentermine (Adipex P, Ionamin)
  • ritonavir (Norvir)
  • sedatives
  • selective serotonin reuptake inhibitors (SSRIs) such as:
    • citalopram (Celexa)
    • escitalopram (Lexapro)
    • fluoxetine (Prozac, Sarafem)
    • fluvoxamine (Luvox)
    • paroxetine (Paxil)
    • sertraline (Zoloft)
  • sibutramine (Meridia)
  • sleeping pills
  • tramadol (Ultram)
  • tranquilizers
Tell your health care provider:
  • if you are allergic to venlafaxine, any other medications, or any of the ingredients in venlafaxine tablets or extended-release capsules. Ask your pharmacist for a list of the ingredients
  • what other prescription and nonprescription medications, and vitamins you are taking or plan to take
  • what nutritional supplements and herbal products you are taking, especially St. John's wort and tryptophan
  • if you have ever used illegal drugs or overused prescription medications
  • if you have recently had a heart attack and if you have or have ever had high blood pressure, high blood cholesterol glaucoma (an eye disease), high pressure in the eyes (a condition that can lead to glaucoma), seizures, or heart, kidney, liver, or thyroid disease
  • if you are pregnant or if you plan to become pregnant, venlafaxine may cause problems in newborns following delivery if it is taken during the last months of pregnancy
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking venlafaxine
  • if you are are breast-feeding
This medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. Alcohol can add to the drowsiness caused by this medication.

Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Overdose Information:
Contact 1-800-222-1222 (the American Association of Poison Control Centers) or your local poison control center, or call 911. Overdose symptoms may include:
  • dizziness
  • nausea
  • vomiting
  • burning, tingling, or numbness of the hands and feet
  • increased size of the pupil (black center of the eye)
  • muscle pain
  • hot and cold spells
  • sleepiness
  • seizures
  • fast, slow, or irregular heartbeat
  • coma (loss of consciousness for a period of time)
Missed Dose:
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are taking the extended-release capsules, do not take more than one dose per day.

Storage:
Store venlafaxine at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom.

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