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Topiramate (generic Topamax)


Topiramate (generic Topamax) is an anticonvulsant used to treat certain types of seizures in people who have epilepsy. It is also widely used as a preventative for migraines due to the effect it has on widening the blood vessels in the brain which become restricted by increased serotonin levels. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is used to treat patients who continue to have seizures even when they take other antiseizure medications. Topiramate is also used for the management of alcohol dependence, methamphetamine addiction, cocaine addiction, obesity and antipsychotic-induced weight gain.

Quantity/Dose Price Medical Services Fee Shipping Total
30  25mg Tablet$ 10.00$ 39.95$ 4.99$ 54.94
60  25mg Tablet$ 15.00$ 39.95$ 4.99$ 59.94
90  25mg Tablet$ 20.00$ 39.95$ 4.99$ 64.94
30  50mg Tablet$ 15.00$ 39.95$ 4.99$ 59.94
60  50mg Tablet$ 20.00$ 39.95$ 4.99$ 64.94
30  100mg Tablet$ 18.00$ 39.95$ 4.99$ 62.94

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IMPORTANT NOTE: This information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other health care provider. It should not be construed to indicate that the use of the medication(s) shown are safe, appropriate, or effective for you. The information shown is general and does not cover all directions, possible drug integrations, or precautions. Information on this site cannot be used for self-treatment and/or self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care provider. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site nor will we be held responsible for consequences of self-treatment. Consult your health care provider before using any drug.

Drug Facts for Topiramate / Generic Topamax

Alternate Names:
Topamax

Uses:
Topiramate (generic Topamax) is an anticonvulsant used to treat certain types of seizures in people who have epilepsy. It is also widely used as a preventative for migraines due to the effect it has on widening the blood vessels in the brain which become restricted by increased serotonin levels. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is used to treat patients who continue to have seizures even when they take other antiseizure medications. Topiramate is also used for the management of alcohol dependence, methamphetamine addiction, cocaine addiction, obesity and antipsychotic-induced weight gain.

How to Use:
Topiramate comes as a tablet and a sprinkle capsule (capsule that contains small beads of medication that can be sprinkled on food) to take by mouth. It is usually taken with or without food twice a day in the morning and evening. Take topiramate at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take topiramate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
There is another medication with a name similar to the brand name for topiramate. You should be sure that you receive topiramate and not the similar medication each time you fill your prescription. Be sure that the prescription your doctor gives you is clear and easy to read. Talk to your pharmacist to be sure that you are given topiramate. After you receive your medication, compare the tablets to the pictures in the manufacturer's patient information sheet. If you think you were given the wrong medication, talk to your pharmacist. Do not take any medication unless you are certain it is the medication that your doctor prescribed.
Topiramate tablets have a bitter taste so you should swallow them whole. Do not split, chew, or crush them. It is especially important that you not take topiramate tablets that have been broken for any length of time because tablets that are broken may lose their effectiveness over time.
Your doctor will probably start you on a low dose of topiramate and gradually increase your dose, not more than once every week.
Topiramate may control your seizures or migraines but will not cure your condition. Continue to take topiramate even if you feel well. Do not stop taking topiramate without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking topiramate, you may have severe seizures, even if you have not had seizures in the past. Your doctor will probably decrease your dose gradually.
The sprinkle capsules may be swallowed whole or opened and poured over food. To take the sprinkle capsule with food, follow these steps:
  1. Prepare a teaspoonful of soft food such as applesauce, custard, ice cream, oatmeal, pudding, or yogurt.
  2. Hold the capsule upright over the food. You should be able to read the word 'TOP' on the capsule.
  3. Twist off the clear part of the capsule and pour the entire contents onto the spoonful of food.
  4. Swallow the entire mixture immediately without chewing.
  5. Drink fluids right after swallowing to wash down the mixture and to be sure that you swallow all of it.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with topiramate and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs) or the manufacturer's website to obtain the Medication Guide.

What special dietary instructions should I follow?
Talk to your doctor about increasing the amount of food you eat if you lose weight while you are taking topiramate.

Talk to your doctor before changing your diet or beginning any type of weight loss program. Do not follow a ketogenic diet (a high-fat, low-carbohydrate diet used to control seizures) or any other high-fat, low-carbohydrate diet, such as the Atkins diet, while you are taking this medication.

Side Effects:
Topiramate may cause other side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • numbness, burning, or tingling in the hands or feet
  • slowed reactions
  • difficulty concentrating
  • speech problems, especially difficulty thinking of specific words
  • memory problems
  • lack of coordination
  • confusion
  • nervousness
  • aggressive behavior
  • irritability
  • mood swings
  • depression
  • headache
  • drowsiness
  • weakness
  • excessive movement
  • uncontrollable shaking of a part of the body
  • uncontrollable eye movements
  • extreme thirst
  • weight loss
  • constipation
  • diarrhea
  • gas
  • heartburn
  • change in ability to taste food
  • swelling of the tongue
  • overgrowth of the gums
  • dry mouth
  • increased saliva
  • trouble swallowing
  • nosebleed
  • teary or dry eyes
  • back, muscle, or bone pain
  • missed menstrual periods
  • excessive menstrual bleeding
  • skin problems or changes in skin color
  • dandruff
  • hair loss
  • growth of hair in unusual places
  • ringing in the ears
  • difficulty falling or staying asleep
  • swelling of the hands, arms, feet, ankles, or lower legs
  • difficulty urinating or pain when urinating
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
  • blurred vision
  • double vision
  • eye pain
  • worsening of seizures
  • slow heart rate
  • pounding or irregular heartbeat
  • chest pain
  • trouble breathing
  • fast, shallow breathing
  • inability to respond to things around you
  • excessive tiredness
  • nausea
  • vomiting
  • stomach pain
  • loss of appetite
  • intense back or side pain
  • bloody, cloudy, or foul-smelling urine
  • constant need to urinate
  • fever
  • chills
Topiramate may cause osteoporosis (a condition in which bones can break more easily) in adults and rickets (abnormal, curved bone growth) in children. Topiramate may also slow the growth of children and may decrease the final height that children reach.
Topiramate may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Precautions:
Tell your doctor and pharmacist if you are allergic to topiramate or any other medications.
Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following:
  • acetazolamide (Diamox)
  • amitriptyline
  • antidepressants
  • antihistamines
  • dichlorphenamide (Daranide)
  • digoxin (Lanoxin, Digitek)
  • hydrochlorothiazide (Microzide, Oretic)
  • ipratropium (Atrovent)
  • iron
  • isoniazid (INH, Nydrazid)
  • lithium (Eskalith, Lithobid)
  • medications for anxiety, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, ulcers, or urinary problems
  • metformin (Glucophage)
  • methazolamide
  • hormonal contraceptives (birth control pills, patches, rings, implants, or injections)
  • other medications for seizures such as carbamazepine (Tegretol) and phenytoin (Dilantin, Phenytek)
  • pioglitazone (Actos)
  • risperidone (Risperdal)
  • salicylate pain relievers such as aspirin, choline magnesium trisalicylate (Trisalate), choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, others), and salsalate (Argesic, Disalcid, Salgesic)
  • sedatives
  • sleeping pills
  • tranquilizers
  • valproic acid (Depakene, Depakote)
  • zonisamide (Zonegran)
Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Tell your doctor if you or any family members have or have ever had kidney stones, if you drink or have ever drunk large amounts of alcohol, and if you have ever thought about killing yourself or tried to do so. Also tell your doctor if you have or have ever had:
  • metabolic acidosis (a disturbance in the body's acid-base balance that results in excessive acidity of the blood)
  • osteopenia, osteomalacia, or osteoporosis (conditions in which the bones are soft or brittle and may break easily)
  • diabetes
  • glaucoma (a type of eye disease)
  • any disease that affects your breathing such as asthma or chronic obstructive pulmonary disease (COPD)
  • depression or abnormal moods
  • a growth problem
  • liver or kidney disease
Also tell your doctor if you have diarrhea or if you develop diarrhea during your treatment.

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you are pregnant or plan to become pregnant, your doctor may prescribe a different medication instead of topiramate because topiramate may harm the fetus. If you do not plan to become pregnant, you should use birth control to prevent pregnancy during your treatment with topiramate. Talk to your doctor about what type of birth control you should use, because taking topiramate may decrease the effectiveness of some types of birth control. If you become pregnant while you are taking topiramate, call your doctor right away, but do not stop taking topiramate before talking to your doctor.

If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking topiramate.

Topiramate may make you drowsy, dizzy, confused, or unable to concentrate. Do not drive a car or operate machinery until you know how this medication affects you.

If you are taking topiramate to control seizures, you should know that you may continue to have seizures during your treatment. You may need to avoid activities such as swimming, driving, and climbing so that you will not harm yourself or others if you lose consciousness during a seizure.

Ask your doctor about the safe use of alcoholic beverages while you are taking topiramate.

Topiramate can prevent you from sweating and make it harder for your body to cool down when it gets very hot. This happens most often in warm weather and to children who take topiramate. Avoid exposure to heat, drink plenty of fluids and tell your doctor if you have a fever, headache, muscle cramps, or an upset stomach, or if you are not sweating as usual.

You may be more likely to develop a kidney stone while you are taking topiramate. Drink 6 to 8 glasses of water every day to prevent kidney stones from forming.

Your mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking topiramate for the treatment of epilepsy, mental illness, or other conditions. A small number of adults and children 5 years of age and older (about 1 in 500 people) who took anticonvulsants such as topiramate to treat various conditions during clinical studies became suicidal during their treatment. Some of these people developed suicidal thoughts and behavior as early as 1 week after they started taking the medication. There is a risk that you may experience changes in your mental health if you take an anticonvulsant medication such as topiramate, but there may also be a risk that you will experience changes in your mental health if your condition is not treated. You and your doctor will decide whether the risks of taking an anticonvulsant medication are greater than the risks of not taking the medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms:
  • panic attacks
  • agitation or restlessness
  • new or worsening irritability, anxiety, or depression
  • acting on dangerous impulses
  • difficulty falling or staying asleep
  • aggressive, angry, or violent behavior
  • mania (frenzied, abnormally excited mood)
  • talking or thinking about wanting to hurt yourself or end your life
  • withdrawing from friends and family; preoccupation with death and dying
  • giving away prized possessions
  • any other unusual changes in behavior or mood
Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Overdose Information:
Contact 1-800-222-1222 (the American Association of Poison Control Centers) or your local poison control center, or call 911. Overdose symptoms may include:
  • seizures
  • drowsiness
  • speech problems
  • blurred vision
  • double vision
  • trouble thinking
  • tiredness
  • loss of coordination
  • loss of consciousness
  • dizziness
  • stomach pain
  • vomiting
  • agitation
  • depression
  • loss of appetite
  • pounding or irregular heartbeat
  • fast, shallow breathing
Missed Dose:
Take the missed dose as soon as you remember it. However, if it is less than 6 hours before you are scheduled to take your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage:
Store topiramate at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, light, and moisture. Do not store in the bathroom.

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