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Diflucan (fluconazole)


Diflucan is used to treat fungal infections called candidiasis (also known as thrush or yeast infections). These include vaginal infections, throat infections, and fungal infections elsewhere in the body, such as infections of the urinary tract, peritonitis (inflammation of the lining of the abdomen), and pneumonia.

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IMPORTANT NOTE: This information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other health care provider. It should not be construed to indicate that the use of the medication(s) shown are safe, appropriate, or effective for you. The information shown is general and does not cover all directions, possible drug integrations, or precautions. Information on this site cannot be used for self-treatment and/or self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care provider. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site nor will we be held responsible for consequences of self-treatment. Consult your health care provider before using any drug.

What is Diflucan?
Diflucan is the brand name for the drug Fluconazole. Diflucan is an antifungal type of antibiotic. It treats serious fungal infections found throughout the body. These include oral candidiasis or thrush infections of the mouth or throat, vaginal yeast infections, candidal infection of the urinary tract, meningitis, and others.

What should my health care professional know before I take Diflucan?
They need to know if you have any of these conditions:
  • diabetes
  • heart disease
  • kidney disease
  • liver disease
  • other chronic illness
  • an unusual or allergic reaction to Diflucan, other azole medicines (used to treat fungal or yeast infections), or other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding


  • How should I take Diflucan?
    Take Diflucan oral suspension or tablets by mouth. Follow the directions on the prescription label. If taking the oral suspension, shake it well before using. Use a specially marked spoon or container to measure the oral suspension. Ask your pharmacist if you do not have one; household spoons are not always accurate. You can take the oral suspension or tablets with or without food. Take your doses at regular intervals. Do not take Diflucan more often than directed. Finish the full course prescribed by your health care professional even if you feel better. Do not stop taking except on your prescriber's advice.

    What if I miss a dose of Diflucan?
    If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

    What drug(s) may interact with Diflucan?
  • bosentan
  • cilostazol
  • cisapride
  • cyclosporine
  • dofetilide
  • doxercalciferol
  • certain medicines for anxiety or difficulty sleeping
  • medicines for diabetes that are taken by mouth
  • medicines for high cholesterol such as atorvastatin, fluvastatin, lovastatin, or simvastatin
  • medicines for yeast or fungal infections
  • paricalcitol
  • phenytoin
  • pimozide
  • ramelteon
  • rifabutin
  • rifampin
  • tacrolimus
  • terfenadine
  • warfarin
  • water pills


  • Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Diflucan works. Check with your health care professional before stopping or starting any of Diflucans.

    What side effects may I notice from taking Diflucan?
    Stop taking Diflucan immediately and report these side effects to your prescriber or health care professional right away:
  • fainting or falling spells
  • irregular heartbeat, palpitations, or chest pain


  • Diflucan Side effects that you should report to your prescriber or health care professional as soon as possible:
  • dark yellow or brown urine
  • dizziness
  • light-colored stools (bowel movements)
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • skin rash, itching
  • stomach pain
  • unusual bruising or bleeding
  • yellowing of the eyes or skin
  • vomiting


  • Diflucan Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
  • diarrhea
  • headache
  • loss of appetite or changes in how food tastes
  • nausea


  • What should I watch for while taking Diflucan?
    Tell your prescriber or health care professional if your symptoms do not improve in a few weeks. Some fungal infections need many weeks or months of treatment to cure. Keep taking Diflucan regularly for as long as your prescriber or health care professional tells you to. If you are taking Diflucan for a long time you must visit your prescriber or health care professional for regular blood and liver function tests. Alcohol can increase possible damage to your liver. Do not take alcoholic drinks while you take Diflucan. If you have a vaginal infection, do not have sex until you have finished your treatment. Your clothing may get soiled if you have a vaginal discharge. You can wear a sanitary napkin; do not use tampons. Wear freshly washed cotton, not synthetic, panties.

    Diflucan has been associated with birth defects when given at high doses early in a pregnancy. If you are pregnant or think you may be pregnant, tell you prescriber or health care professional immediately. Women who may become pregnant should use effective birth control while taking Diflucan.

    Where can I keep Diflucan?
    Keep out of the reach of children in a container that small children cannot open. Store at room temperature below 30C (86F). Keep container tightly closed. Throw away any unused Diflucan after the expiration date.

    Where can I get more Diflucan information?
    Visit the Diflucan Website

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